A. 1 L/kg
B. 7 L/kg
C. 10 L/kg
D. 14 L/kg
CHECK ANSWER
The correct answer is A. 1 L/kg
KR2250 is an investigational cholesterol-lowering agent. KR2250 has a high molecular weight and is extensively bound to albumin. KR2250 will have a(n) ___ apparent volume of distribution (Vd).
A. High
B. Low
C. Extremely high
D. Normal
CHECK ANSWER
The correct answer is C. Extremely high
Drug A is a weakly basic drug with a pKa of 7.8. If administered orally, at which of the following sites of absorption will the drug be able to readily pass through the membrane?
A. Mouth (pH approximately 7.0)
B. Stomach (pH of 2.5)
C. Duodenum (pH approximately 6.1)
D. Jejunum (pH approximately 8.0)
CHECK ANSWER
The correct answer is D. Jejunum (pH approximately 8.0)
An 18-year-old female patient is brought to the emergency department due to a drug overdose. Which of the following routes of administration is the most desirable for administering the antidote for the drug overdose?
A. Intramuscular
B. Intravenous
C. Oral
D. Subcutaneous
CHECK ANSWER
The correct answer is B. Intravenous